Approximately 15.5 million Americans have a history of cancer, with an estimated 1,688,780 new cases and 609,640 deaths annually. With 87% of diagnoses occurring in persons 50 years of age, cancer remains the second leading cause of death in the United States. Cancer’s financial burden is often substantial during treatment phases and often worsens with improving prognoses. Cancer’s direct medical costs in the United States exceed $80 billion and indirect costs of premature morbidity and mortality exceed $130 billion. With 6.5% of direct costs among non-elderly persons alone involving out-of-pocket payments, over half of all persons with cancer experienced house repossession, bankruptcy, loss of independence, and relationship breakdowns. See more: